Our Technologies Include:

²  Asymmetric Synthesis Technology

 ü   Enzymatic transformation(Chiral amine, Chiral alcohol, Un-nature amino acid)

 ü   Asymmetric hydrogenation

 ü   Chiral auxiliary (Chiral sulfinamide, Evan’s Auxiliary etc) asymmetric synthesis

ü   Chemical Resolution with chiral acid or amine

 ²  Coupling Technology

 Suzuki coupling, Buchwald reaction, Sonogashira reaction, Negishi reaction, Heck reaction , Stille reaction,  Cu Nickel catalyzed C-C, C-N, C-O coupling are widely applied in our research and production. 

 ²  Grignard Reaction

    With extensive experience, we can carry out up to 10000L Grignard reaction

Our Service Includes:

Custom Synthesis Service

 - Medicinal chemistry scaffold and building blocks
- Scale-up of selected compounds for further evaluation
- Reference compound, assay standard, and metabolite
- Key and advanced intermediates
- Synthetic pathway design, evaluation and route scouting

Process R & D and Production

 - Research and development of chemical processes suitable for the synthesis of preclinical and phase I/II study materials from the original medicinal chemistry route
- Process improvement of existing chemical process
- Validation of process technical package provided by customers
- Production of non-GMP material and advanced intermediates up to hundreds of kilograms